U.S. Department of Health and Human Services Recommends

Patient Counseling Information Avanafil

“See FDA-approved patient labeling (Patient Information)”

Nitrates

Physicians should check with patients the contraindication of with regular and/or intermittent usage of organic nitrates. Patients should be counseled that concomitant usage of with nitrates may cause blood pressure to suddenly drop to a unsafe level, ultimately causing dizziness, syncope, and in many cases cardiac event or stroke.

Physicians should consult with patients the suitable action while in the event that they can experience anginal heart problems requiring nitroglycerin following intake of . Within this particular patient, who's taken , where nitrate administration is deemed medically necessary inside the life-threatening situation, at the very least 12 hours should elapse following on on the last dose of before nitrate administration is considered. Such circumstances, nitrates should still only be administered under close medical supervision with appropriate hemodynamic monitoring. Patients who experience anginal heart related illnesses after taking should seek immediate medical attention [see Contraindications and Warnings and Precautions].

Cardiovascular Considerations

Physicians should discuss with patients the wide ranging cardiac risk of sexual acts in patients with preexisting cardiovascular risk factors. Patients who experience symptoms upon initiation of sex need to be advised to stop talking further sex and may seek immediate medical attention [see Warnings and Precautions].

Concomitant Use with Drugs Which Lower Bp

Physicians should advise patients inside potential for to augment hypertension-lowering effect of alpha-blockers as well as other antihypertensive medications [see Warnings and Precautions , Drug Interactions , and Clinical Pharmacology].

Chance of Drug Interactions

Patients really should be advised to make contact with the prescribing physician if new medications that will communicate with are prescribed by another healthcare provider.

Priapism

There was rare reports of prolonged erections greater than 4 hours and priapism (painful erections above 6 hours in duration) as a result class of compounds. Priapism, usually treated promptly, may cause irreversible trouble for any erectile tissue. Physicians should advise patients using a hardon lasting greater than 4 hours, whether painful or maybe you cannot, to hunt emergency medical attention.

Vision

Physicians should advise patients to prevent using all PDE5 inhibitors, including , and seek medical attention within the event of a sudden loss in vision per or both eyes. These types of event in many cases are a sign of non-arteritic anterior ischemic optic neuropathy (NAION), a contributing factor to decreased vision including permanent decrease of vision that was reported rarely in temporal association while using PDE5 inhibitors. You cannot determine whether these events are related on to the utilization of PDE5 inhibitors so as to other elements. Physicians should likewise seek advice from patients the raised risk of NAION in individuals with already experienced NAION in a single eye, including whether such individuals can be adversely relying on using vasodilators, similar to PDE5 inhibitors [see Adverse Reactions ].

Sudden Diminished hearing

Physicians should advise patients avoiding taking PDE5 inhibitors, including , and seek prompt medical help in case of sudden decrease or loss of hearing. Make full use of PDE5 inhibitors might be regarding sudden decrease or loss in hearing, that is along with tinnitus and dizziness. You cannot discover whether these events are associated on to the use of PDE5 inhibitors so as to variables [see Adverse Reactions ].

Alcohol

Patients should be made conscious both alcohol and PDE5 inhibitors including work as mild vasodilators. When mild vasodilators are consumed together, blood pressure levels-lowering connection in between each individual compound may perhaps be increased. Therefore, physicians should inform patients that substantial consumption of alcohol (e.g., well over 3 units) in conjunction with can improve the probability of orthostatic signs and symptoms, including surge in pulse, lessing of standing blood pressure, dizziness, and headache. [see Warnings and Precautions and Clinical Pharmacology].

Std

Using offers no protection against std's. Counseling of patients regarding the protective measures vital that you guard against std's, including HIV (HIV) may be useful.

Recommended Administration

Physicians should contact patients the right using as well as its anticipated benefits. It should be explained that sexual stimulation is necessary for tougher erection to happen after taking . have to be taken approximately an hour before initiating sex. Patients should be counseled in connection with dosing of . Inform patients the recommended starting dose of is 100 mg. The dose could be increased on your maximum recommended dose of 200 mg or decreased to 50 mg based upon efficacy and tolerability. The smallest dose that offers benefit must be used. Patients ought to be advised to make contact with their healthcare provider for dose modification.

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